Agony of Christ

[Agony in the Garden] The word agony is used only once in Scripture, in Luke, 22:43, to designate the anguish of Christ in the Garden of Gethsemani. The incident is narrated also in Matthew and Mark, but only Luke mentions the sweat of blood and the visitation of the angel. The sweat of blood is understood literally by almost all Catholic interpreters; medical testimony has been alleged that such a phenomenon, though rare, is neither impossible nor preternatural.

New Catholic Dictionary

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